Mature (adult) and immature (L4): Haemonchus contortus (Barbers pole worm), Trichostrongylus spp (Black scour worm), Trichostrongylus axei (Stomach hair worm) Trichostrongylus colubriformis, Ostertagia (Teladorsagia) spp (Small brown stomach worm), Teladorsagia circumcincta, Cooperia spp (Small intestinal worm), Cooperia oncophora, Nematodirus spp (Thin necked intestinal worm), Nematodirus battus, Nematodirus fillicollis, Nematodirus spathiger, Strongyloides papillosus (Intestinal threadworm), Oesophagostomum columbianum (Nodule worm), Chabertia ovina (Large mouthed bowel worm), Dictyocaulus filaria (Large lungworm).
Adult nematodes: Trichostrongylus rugatus, Trichostrongylus vitrinus, Cooperia curticei, Nematodirus abnormalis, Nematodirus helvetianus, Teladorsagia trifurcate, Oesophagostomum venulosum Large bowel worm, Trichuris ovis.
Ectoparasites: Psorergates ovis itchmite. When used as recommended, Sheepguard SE prevents reinfection with H. contortus worms for at least 14 days and pasture contamination by H. contortus eggs for at least 30 days after single treatment. It also prevents re-infection by Teladorsagia sp. worms for at least 14 days and pasture contamination by Teladorsagia sp. eggs for at least 35 days after a single treatment. It is effective against benzimidazole and levamisole resistant strains of H. contortus, T. colubriformis and T. circumcincta. It has shown efficacy against a number of ivermectin resistant strains of H. contortus and Teladorsagia sp. However, as Sheepguard shares similar mechanism of action to the avermectins, it should not be used where avermectin resistance is present, except where specifically recommended by an advisor.